HIP55 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA589408-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA589408 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
HIP55
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DBNL
Gene Alias
Abp1, Actin-binding protein 1, cervical mucin-associated protein, Cervical SH3P7, CMAP, DBNL, dbnl {ECO:0000312, drebrin F, drebrin like, drebrin-F, drebrin-like, drebrin-like protein, EMBL:AAH72483.1}, HIP55, HIP-55, HPK1-interacting protein of 55 kDa, mAbp1, PP5423, SH3 domain-containing protein 7, Sh3p7, src homology 3 domain-containing protein HIP-55
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
13169, 28988, 83527
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
2.72 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
Q62418, Q9JHL4, Q9UJU6
Gene Symbols
DBNL
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 131-430 of human DBNL (NP_0010144361)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: KVAKASGANY SFHKESGRFQ DVGPQAPVGS VYQKTNAVSE IKRVGKDSFW AKAEKEEENR RLEEKRRAEE AQRQLEQERR ERELREAARR EQRYQEQGGE ASPQRTWEQQ QEVVSRNRNE QESAVHPREI FKQKERAMST TSISSPQPGK LRSPFLQKQL TQPETHFGRE PAAAISRPRA DLPAEEPAPS TPPCLVQAEE EAVYEEPPEQ ETFYEQPPLV QQQGAGSEHI DHHIQGQGLS GQGLCARALY DYQAADDTEI SFDPENLITG IEVIDEGWWR GYGPDGHFGM FPANYVELIE; Positive Samples: HeLa, MCF-7, Jurkat, K-562, Mouse brain, Mouse thymus, Mouse spleen, Mouse testis, Rat heart; Cellular Location: Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Golgi apparatus membrane, Peripheral membrane protein, cell cortex, clathrin-coated vesicle membrane, cytoskeleton, cytosol, lamellipodium, podosome, ruffle, synapse The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication
- The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins
- The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme
- The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex
- This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks
- Alternatively spliced transcript variants encoding the same protein have been reported.