PIPA589567

HOXA13 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA589567-Each-of-1 In Stock ₹ 46,502.50

PIPA589567 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

HOXA13

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Hoxa13

Gene Alias

Hd, homeo box 1J, homeo box A13, homeobox A13, homeobox protein Hox-1.10, Homeobox protein Hox-1J, homeobox protein HOXA13, homeobox protein Hox-A13, HOX1, Hox-1.10, HOX1J, HOXA13, hypodactyly, RGD1562483, transcription factor HOXA13

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3209

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

2.42 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

P31271

Gene Symbols

Hoxa13

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 140-320 of human HOXA13 (NP_0005132)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: GPAGPAGAEA AKQCSPCSAA AQSSSGPAAL PYGYFGSGYY PCARMGPHPN AIKSCAQPAS AAAAAAFADK YMDTAGPAAE EFSSRAKEFA FYHQGYAAGP YHHHQPMPGY LDMPVVPGLG GPGESRHEPL GLPMESYQPW ALPNGWNGQM YCPKEQAQPP HLWKSTLPDV VSHPSDASSY R; Positive Samples: 22RV1, HT-29; Cellular Location: Nucleus HoxA13 and HoxD13 also bind to other BMP and TGF-beta/Activin-regulated Smad proteins including Smad1 and Smad2, but not Smad4
  • In humans and mice, loss of HOXA13 function causes defects in the growth and patterning of the digits and interdigital tissues
  • Analysis of HoxA13 expression reveals a pattern of localization overlapping with sites of reduced Bmp2 and Bmp7 expression in HoxA13 mutant limbs
  • HoxA13 regulates Bmp2 and Bmp7 expression, providing a link between HoxA13, its target genes and the specific developmental processes affected by loss of HoxA13 function.