GPNMB Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA589716-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA589716 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
GPNMB
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GPNMB
Gene Alias
Dchil, DC-HIL, dendritic cell-associated heparin sulfate proteoglycan-dependent integrin ligand, dendritic cell-associated transmembrane protein, glycoprotein (transmembrane) nmb, glycoprotein nmb, glycoprotein nmb-like protein, glycoprotein nonmetastatic melanoma protein B, Gpnmb, hematopoietic growth factor inducible neurokinin-1, Hematopoietic growth factor inducible neurokinin-1 type, Hgfin, ipd, iris pigment dispersion, NMB, Osteoactivin, si:ch211-155k24.6, transmembrane glycoprotein HGFIN, transmembrane glycoprotein NMB, Unknown (protein for MGC:133733), UNQ1725/PRO9925
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10457, 113955, 93695
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
2.25 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
Q14956, Q6P7C7, Q99P91
Gene Symbols
GPNMB
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 23-486 of human GPNMB (NP_0010053401)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: A-549, K-562, U-87MG, Mouse brain, Mouse liver, Rat brain, Rat liver; Cellular Location: Cell membrane, Melanosome, Single-pass type I membrane protein Immunogen sequence: KRFHDVLGNE RPSAYMREHN QLNGWSSDEN DWNEKLYPVW KRGDMRWKNS WKGGRVQAVL TSDSPALVGS NITFAVNLIF PRCQKEDANG NIVYEKNCRN EAGLSADPYV YNWTAWSEDS DGENGTGQSH HNVFPDGKPF PHHPGWRRWN FIYVFHTLGQ YFQKLGRCSV RVSVNTANVT LGPQLMEVTV YRRHGRAYVP IAQVKDVYVV TDQIPVFVTM FQKNDRNSSD ETFLKDLPIM FDVLIHDPSH FLNYSTINYK WSFGDNTGLF VSTNHTVNHT YVLNGTFSLN LTVKAAAPGP CPPPPPPPRP SKPTPSLATT LKSYDSNTPG PAGDNPLELS RIPDENCQIN RYGHFQATIT IVEGILEVNI IQMTDVLMPV PWPESSLIDF VVTCQGSIPT EVCTIISDPT CEITQNTVCS PVDVDEMCLL TVRRTFNGSG TYCVNLTLGD DTSLALTSTL ISVP The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein
- GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines
- GPNMB may be involved in growth delay and reduction of metastatic potential
- Two transcript variants encoding different isoforms have been found for this gene.