FGF4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA590007-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA590007 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
FGF4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Fgf4
Gene Symbols
Fgf4
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 31-206 of human FGF4 (NP_0019981)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Rat
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Concentration
1.32 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Alias
FGF, FGF4, Fgf-4, Fgfk, Fibroblast growth factor, fibroblast growth factor 4, fibroblast growth factor 4 splice isoform, HBGF-4, heparin secretory transforming protein 1, heparin secretory-transforming protein 1, heparin-binding growth factor 1, heparin-binding growth factor 4, HST, Hst1, hst-1, HSTF1, HSTF-1, human stomach cancer, transforming factor from FGF-related oncogene, kaposi sarcoma oncogene, Kfgf, K-FGF, K-fibroblast growth factor, KS3, oncogene HST, transforming protein KS3
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
116499
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
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Description
- Immunogen sequence: APTAPNGTLE AELERRWESL VALSLARLPV AAQPKEAAVQ SGAGDYLLGI KRLRRLYCNV GIGFHLQALP DGRIGGAHAD TRDSLLELSP VERGVVSIFG VASRFFVAMS SKGKLYGSPF FTDECTFKEI LLPNNYNAYE SYKYPGMFIA LSKNGKTKKG NRVSPTMKVT HFLPRL; Positive Samples: Rat liver Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis
- FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain
- Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway
- Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation
- Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.