STAT1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595442-Each-of-1 | In Stock | ₹ 47,392.50 |
PIPA595442 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,392.50
GST (18%): ₹ 8,530.65
Total Price: ₹ 55,923.15
Antigen
STAT1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
STAT1
Gene Alias
2010005J02Rik, AA408197, CANDF7, DD6G4-4, DKFZp686B04100, IMD31A, IMD31B, IMD31C, ISGF-3, LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta, OTTHUMP00000165046, OTTHUMP00000205845, signal transducer and activator of transcription 1, signal transducer and activator of transcription 1, 91kD, signal transducer and activator of transcription 1, 91kDa, signal transducer and activator of transcription 1-alpha/beta, signal transducer and activator of transcription-1, STAT, STAT 1, STAT1, STAT-1, stat1 alpha, STAT91, transcription factor ISGF-3, transcription factor ISGF-3 components p91/p84
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20846, 25124, 6772
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Lyophilized
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration
500 μg/mL
Formulation
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.
P42224, P42225
Gene Symbols
STAT1
Immunogen
E.coli-derived human STAT1 recombinant protein (Position: S2-A230).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Human STAT1 shares 91.2% amino acid (aa) sequence identity with mouse STAT1
- Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
- STAT1 (signal transducers and activators of transcription 1) is a member of the STAT family of transcription factors
- STAT1 can be activated by interferon-alpha, interferon-gamma, EGF, PDGF and IL6
- STAT1 is known to regulate several genes which are involved in cell growth, apoptosis, immune responses, and lipid metabolism
- Further, STAT1 plays an important role in mediating cell viability in response to different cell stimuli and pathogen exposure
- The STAT1 gene is located on chromosome 2
- STAT1 is activated to regulate gene expression in response to extracellular signaling polypeptides including cytokines, interferons, and growth factors
- After phosphorylation by JAK tyrosine kinases, STAT1 enters the nucleus to regulate transcription of many different genes
- Among the seven STATs types, STAT1, STAT3, STAT5a, and STAT5b have a wide activation profile
- STAT1 is activated by many different ligands including IFN family (IFN-Alpha, IFN-Beta, IFN-gamma and IL-10), gp130 family (IL-6, IL-11, LIF, CNTF, and G-CSF), and receptor tyrosine kinases (EGF, PDGF, and CSF-1)
- Two alternatively spliced transcript variants encoding distinct isoforms of STAT1 have been described.