STAR Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595765-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA595765 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
STAR
Classification
Polyclonal
Conjugate
Unconjugated
Gene
STAR
Gene Alias
AV363654, cholesterol trafficker, D8Ertd419e, lipid transporter, luteinizing hormone-induced protein, mitochondrial steroid acute regulatory protein, STAR, StAR related lipid transfer (START) domain containing 1, stARD1, StAR-related lipid transfer (START) domain containing 1, START domain containing 1, START domain-containing protein 1, steroid acute regulatory protein, steroidogenic acute regulator, steroidogenic acute regulatory protein, steroidogenic acute regulatory protein, mitochondrial, testis secretory sperm-binding protein Li 241mP
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20845, 25557, 6770
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
2.56 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.
P49675, P51557, P97826
Gene Symbols
STAR
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 64-285 of human StAR (NP_0003402)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: K-562, Mouse ovary, Rat testis; Cellular Location: Mitochondrion Immunogen sequence: EETLYSDQEL AYLQQGEEAM QKALGILSNQ EGWKKESQQD NGDKVMSKVV PDVGKVFRLE VVVDQPMERL YEELVERMEA MGEWNPNVKE IKVLQKIGKD TFITHELAAE AAGNLVGPRD FVSVRCAKRR GSTCVLAGMA TDFGNMPEQK GVIRAEHGPT CMVLHPLAGS PSKTKLTWLL SIDLKGWLPK SIINQVLSQT QVDFANHLRK RLESHPASEA RC Steroidogenic acute regulatory protein (StAR) plays a significant role in cholesterol transport from the cytoplasmic outer membrane to the inner mitochondrial membrane
- The 37 kDa precursor is cleaved to generate an active 28 kDa protein capable of facilitating cholesterol metabolism into pregnenolone
- StAR is prevalently expressed in mitochondria of steroid-producing adrenal and gonadal tissue
- Abnormalities in StAR gene expression are impacted in autosomal Lipoid Congenial Adrenal Hyperplasia (LCAH) resulting in defects in pregnenolone and cortisol synthesis
- The mechanism of cholesterol binding to StAR has yet to be elucidated.