CD46 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595788-Each-of-1 | In Stock | ₹ 47,036.50 |
PIPA595788 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,036.50
GST (18%): ₹ 8,466.57
Total Price: ₹ 55,503.07
Antigen
CD46
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CD46
Gene Alias
AHUS2, antigen identified by monoclonal antibody TRA-2-10, brain microvascular membrane cofactor, brain microvascular membrane cofactor protein CD46, Cd46, CD46 antigen, complement regulatory protein, CD46 complement regulatory protein, CD46 molecule, CD46 molecule, complement regulatory protein, CD46 splice variant, complement membrane cofactor protein, complement regulatory protein, Mcp, MCP, complement activation regulator, measles virus receptor, membrane cofactor protein, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), membrane cofactor protein variant 10, membrane cofactor protein variant 7, membrane cofactor protein variant 8, membrane cofactor protein variant 9, MGC26544, MIC10, soluble membrane cofactor protein variant 11, soluble membrane cofactor protein variant 12, soluble membrane cofactor protein variant 13, TLX, TRA2.10, trophoblast leucocyte common antigen, trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antig
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17221, 29333, 4179
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.94 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
O88174, P15529, Q9Z0M4
Gene Symbols
CD46
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 40-320 of human CD46 (NP_7225481)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: TFEAMELIGK PKPYYEIGER VDYKCKKGYF YIPPLATHTI CDRNHTWLPV SDDACYRETC PYIRDPLNGQ AVPANGTYEF GYQMHFICNE GYYLIGEEIL YCELKGSVAI WSGKPPICEK VLCTPPPKIK NGKHTFSEVE VFEYLDAVTY SCDPAPGPDP FSLIGESTIY CGDNSVWSRA APECKVVKCR FPVVENGKQI SGFGKKFYYK ATVMFECDKG FYLDGSDTIV CDSNSTWDPP VPKCLKVSTS STTKSPASSA SGPRPTYKPP VSNYPGYPKP E; Positive Samples: Jurkat, Mouse testis, Rat testis; Cellular Location: Cytoplasmic vesicle, Single-pass type I membrane protein, acrosome inner membrane, secretory vesicle CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction
- CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function
- CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.