PIPA595806
YPEL3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595806-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA595806 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
YPEL3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
YPEL3
Gene Alias
0610043B10Rik, 1190001G19Rik, FKSG5, Protein yippee-like 3, RGD1564579, small ubiquitinated apoptotic protein, Suap, yippee like 3, yippee-like 3, yippee-like 3 (Drosophila), YPEL3
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
293491, 66090
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.49 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
P61237
Gene Symbols
YPEL3
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-119 of human YPEL3 (NP_0011389961)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MVRISKPKTF QAYLDDCHRR YSCAHCRAHL ANHDDLISKS FQGSQGRAYL FNSVVNVGCG PAEERVLLTG LHAVADIHCE NCKTTLGWKY EQAFESSQKY KEGKYIIELN HMIKDNGWD; Positive Samples: Rat spleen; Cellular Location: Nucleus, nucleolus YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue
- This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division
- YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence
- It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors.