AKR1C3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595926-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA595926 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
AKR1C3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
AKR1C3
Gene Alias
17-beta-HSD 5, 17beta-HSD5, 17-beta-hydroxysteroid dehydrogenase type 5, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, 20-alpha-hydroxysteroid dehydrogenase, 20alpha-hydroxysteroid dehydrogenase, 2-dih, 3-alpha hydroxysteroid dehydrogenase, type II, 3-alpha-HSD type 2, 3-alpha-HSD type II, brain, 3-alpha-hydroxysteroid dehydrogenase type 2, Akr1c18, AKR1C3, Aldo-keto reductase family 1 member C18, aldo-keto reductase family 1 member C3, aldo-keto reductase family 1, member C18, aldo-keto reductase family 1, member C3, aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II), chlordecone reductase homolog HAKRb, DD3, DD-3, DDH1, DDX, Dihydrodiol dehydrogenase 3, Dihydrodiol dehydrogenase type I, dihydrodiol dehydrogenase X, HA1753, HAKRB, HAKRe, hluPGFS, HSD1, HSD17B5, Indanol dehydrogenase, KIAA0119, PGFS, prostaglandin F synthase, Testosterone 17-beta-dehydrogenase 5, trans-1,2-dihydrobenzene-1,2-diol dehydrogenase, type IIb 3-alpha hydroxysteroid
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
8644
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration
0.74 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
P42330
Gene Symbols
AKR1C3
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human AKR1C3 (NP_0037304)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MDSKHQCVKL NDGHFMPVLG FGTYAPPEVP RSKALEVTKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWSTFH RPELVRPALE NSLKKAQLDY VDLYLIHSPM SLKPGEELSP TDENGKVIFD IVDLCTTWEA MEKCKDAGLA KSIGVSNFNR RQLEMILNKP GLKYKPVCNQ VECHPYFNRS KLLDFCKSKD IVLVAYSALG SQRDKRWVDP NSPVLLEDPV LCALAKKHKR TPALIALRYQ LQRGVVVLAK SYNEQRIRQN VQVFEFQLTA EDMKAIDGLD RNLHYFNSDS FASHPNYPYS DEY; Positive Samples: U-87MG, 293T, LO2, A-549, DU145, Mouse kidney; Cellular Location: Cytoplasm AKR1C3 a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins
- These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors
- The enzymes display overlapping but distinct substrate specificity
- This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9-alpha,11-beta-PGF2 to PGD2
- It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation
- This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.