Iduronate 2 Sulfatase Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA595962-Each-of-1 | In Stock | ₹ 46,057.50 |
PIPA595962 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,057.50
GST (18%): ₹ 8,290.35
Total Price: ₹ 54,347.85
Antigen
Iduronate 2 Sulfatase
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Ids
Gene Alias
alpha-L-iduronate sulfate sulfatase, AW214631, Ids, Iduronate 2-sulfatase, iduronate 2-sulfatase (Hunter syndrome), iduronate 2-sulfatase 14 kDa chain, Iduronate 2-sulfatase 42 kDa chain, iduronate sulfatase, iduronate-2-sulfatase, idursulfase, MPS2, SIDS
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
15931, 3423, 363513
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.2 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.
P22304, Q08890
Gene Symbols
Ids
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 34-290 of human IDS (NP_0001931)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: TDALNVLLII VDDLRPSLGC YGDKLVRSPN IDQLASHSLL FQNAFAQQAV CAPSRVSFLT GRRPDTTRLY DFNSYWRVHA GNFSTIPQYF KENGYVTMSV GKVFHPGISS NHTDDSPYSW SFPPYHPSSE KYENTKTCRG PDGELHANLL CPVDVLDVPE GTLPDKQSTE QAIQLLEKMK TSASPFFLAV GYHKPHIPFR YPKEFQKLYP LENITLAPDP EVPDGLPPVA YNPWMDIRQR EDVQALNISV PYGPIPV; Positive Samples: HepG2, A-549, HT-1080, Mouse kidney, Rat kidney; Cellular Location: Lysosome Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate
- Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome
- Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase
- Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.