GDF5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA597777-Each-of-1 | In Stock | ₹ 46,413.50 |
PIPA597777 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
GDF5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GDF5
Gene Alias
BDA1C, Bmp14, BMP-14, Bone morphogenetic protein 14, bp, brachypodism, brp, Cartilage-derived morphogenetic protein 1, cartilage-derived morphogenetic protein-1, CDMP1, Cdmp-1, GDF5, GDF-5, growth differentiation factor 5, growth/differentiation factor 5, H-GDF-5, LAP4, LAP-4, Lipopolysaccharide-associated protein 4, LPS-associated protein 4, OS5, radotermin, SYM1B, SYNS2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
8200
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Applications
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.39 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
P43026
Gene Symbols
GDF5
Immunogen
Recombinant Human Growth/differentiation factor 5 protein (202-501AA)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- GDF-5 is expressed in long bones during embryonic development and postnatally in articular cartilage
- Mutations in the GDF-5 gene have been implicated in Hunter-Thompson type dwarfism and in Grebe Syndrome, which is characterized by short stature, extra digits, and short and deformed extremities
- The mature and functional form of GDF-5 is a homodimer of two 120 amino-acid polypeptide chain (monomers) linked by a single disulfide bond
- Each GDF-5 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 27 amino acid signal peptide and a 354 amino acid propeptide
- This precursor undergoes intracellular dimerization, and upon secretion it is processed by a furin-type protease.