GFR alpha-1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA597780-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA597780 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
GFR alpha-1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GFRA1
Gene Alias
AU042498, DKFZp313E1012, DKFZp686J0156, FLJ10561, FLJ31546, GDNF family receptor alpha 1, GDNF family receptor alpha-1, GDNF receptor alpha, GDNF receptor alpha-1, GDNFR, GDNFRA, GDNFR-alpha, GDNFR-alpha-1, gfr alpha 1, GFR alpha-1, GFRA1, GFR-alpha-1, glial cell line derived neurotrophic factor family receptor alpha 1, Glial cell line-derived neurotrophic factor receptor alpha, GPI-linked anchor protein, MGC23045, PI-linked cell-surface accessory protein, RET ligand 1, RET1L, RETL1, TGF-beta-related neurotrophic factor receptor 1, TRNR1
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
14585, 2674
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Applications
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
3 mg/mL
Formulation
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4
Gene Accession No.
P56159, P97785
Gene Symbols
GFRA1
Immunogen
Recombinant Human GDNF family receptor alpha-1 protein (230-385AA)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons and is essential for the development of kidneys and the enteric nerves system
- Physiological responses to GDNF require the presence of a novel glycosylphosphadidylinositol linked protein GDNFRalpha, which is a cell surface receptor for GDNF
- The cDNAs encoding GDNFRalpha from human, rat, chicken and mouse have been cloned recently
- GDNFRalpha was also termed Ret ligand 1 (RETL1) or TGF-beta-related neurotrophic factor receptor 1 (TrnR1) and nominated as GFR-a-1 recently
- GFR-a-1 binds GDNF specifically and mediates activation of the Ret protein tyrosine kinase (PTK)
- Thus, GDNF, GFR-a and the Ret PTK form a complex to transduce GDNF signal and to mediate GDNF function.