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PIPA599614

CYP4F2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA599614-Each-of-1 In Stock ₹ 46,502.50

PIPA599614 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

CYP4F2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CYP4F2

Gene Alias

20-HETE synthase; 20-hydroxyeicosatetraenoic acid synthase; Arachidonic acid omega-hydroxylase; CPF2; CYP4F2; CYPIVF2; cytochrome P450 4F2; cytochrome P450 family 4 subfamily F member 2; cytochrome P450, family 4, subfamily F, polypeptide 2; cytochrome P450, subfamily IVF, polypeptide 2; cytochrome P450-LTB-omega; Docosahexaenoic acid omega-hydroxylase; docosahexaenoic acid omega-hydroxylase CYP4F3; phylloquinone omega-hydroxylase CYP4F2; leukotriene-B(4) 20-monooxygenase 1; Leukotriene-B(4) omega-hydroxylase 1; phylloquinone omega-hydroxylase CYP4F2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8529

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P78329

Gene Symbols

CYP4F2

Immunogen

A synthesized peptide derived from human CYP4F2(Accession P78329), corresponding to amino acid residues R46-S96.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Antibody detects endogenous levels of total CYP4F2
  • CYP4F isoforms are involved in the oxidation of important cellular mediators, such as leukotriene B4 (LTB4) and prostaglandins
  • CYP4F2 catalyzes omega-hydroxylation of LTB4 to a less potent proinflammatory eicosanoid, 20-OH-LTB4 as well as arachidonic acid
  • CYP4F2 is expressed in liver and kidney
  • Its expression is repressed by peroxisomal proliferators and induced by retinoic acid
  • X-linked adrenoleukodystrophy (X-ALD) is a severe neurodegenerative disorder biochemically characterized by elevated levels of very long-chain fatty acids (VLCFA)
  • CYP4F2 participates in the omega-hydroxylation of VLCFAs, which may provide an alternative mode of treatment for X-ALD patients.