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PIPA599734

UBE3B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA599734-Each-of-1 In Stock ₹ 46,502.50

PIPA599734 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

UBE3B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

UBE3B

Gene Alias

BPIDS; HECT-type ubiquitin transferase E3B; KOS; UBE3B; UBE3B_v2; ubiquitin protein ligase E3B; ubiquitin-protein ligase E3B

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

89910

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q7Z3V4

Gene Symbols

UBE3B

Immunogen

A synthesized peptide derived from human UBE3B(Accession Q7Z3V4), corresponding to amino acid residues R981-P1031.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Antibody detects endogenous levels of total UBE3B
  • The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation
  • Ubiquitination involves at least three classes of enzymes: E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin-protein ligases
  • This gene encodes a member of the E3 ubiquitin-conjugating enzyme family which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme and transfers the ubiquitin to the targeted substrates
  • A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longer isoform of this protein is the catalytic site of ubiquitin transfer and forms a complex with E2 conjugases
  • Shorter isoforms of this protein which lack the C-terminal HECT domain are therefore unlikely to bind E2 enzymes
  • Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.