PIPA599928

TAS2R38 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA599928-Each-of-1 In Stock ₹ 45,968.50

PIPA599928 - Each of 1

₹ 45,968.50

In Stock

Quantity

1

Base Price: ₹ 45,968.50

GST (18%): ₹ 8,274.33

Total Price: ₹ 54,242.83

Antigen

TAS2R38

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TAS2R38

Gene Alias

mt2r31; PTC; PTC bitter taste receptor; RGD:1560649}; T2R138; T2R26; T2r31; T2r38; T2r38 {ECO:0000312; T2R61; Tas2r138; Tas2r26; TAS2R38; taste 2 receptor member 38; taste receptor type 2 member 26; Taste receptor type 2 member 38; taste receptor type 2 member 61; taste receptor, type 2, member 138; taste receptor, type 2, member 38

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

387513, 500091, 5726

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P59533, Q4VHE7, Q7TQA6

Gene Symbols

Tas2r138, TAS2R38

Immunogen

A synthesized peptide derived from human TAS2R38(Accession P59533), corresponding to amino acid residues L210-S260.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total TAS2R38
  • Receptor that may play a role in the perception of bitterness and is gustducin-linked
  • May play a role in sensing the chemical composition of the gastrointestinal content
  • The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5
  • Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells
  • Variations in TAS2R38 are associated with the ability to taste phenylthiocarbamide (PTC tasting); also called thiourea tasting
  • The ability to taste the substance PTC and a number of related substances is genetically controlled
  • Genetic studies have demonstrated complex inheritance for this trait
  • For some people (and some chimpanzees also), the chemical PTC tastes very bitter
  • For others, it is tasteless
  • Actually, substantial variation in taste sensitivity exists in human
  • Five haplotypes arising from three coding SNPs in the TAS2R38 gene are associated with distinct phenotypes of PTC taste sensitivity.