RB373R1

Myeloperoxidase (MPO) Rabbit Polyclonal Antibody, Epredia™

Manufacturer: Fischer Scientific

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Antigen

Myeloperoxidase (MPO)

Classification

Polyclonal

Conjugate

Unconjugated

Immunogen

Purified human granulocytic MPO

Regulatory Status

IVD

Primary or Secondary

Primary

Form

Ready-to-Use

Applications

Immunohistochemistry (Paraffin)

Clone

Polyclonal

Host Species

Rabbit

Quantity

1 mL

Research Discipline

Enzyme

Target Species

Human, Mouse, Rat

Isotype

IgG

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Description

  • Myeloperoxidase is an important enzyme used by granulocytes during phagocytic lysis of foreign particles engulfed
  • In normal tissues and in a variety of myeloproliferative disorders myeloid cells of both neutrophilic and eosinophilic types, at all stages of maturation, exhibit strong cytoplasmic reactivity for MPO
  • Erythroid precursors, megakaryocytes, lymphoid cells, mast cells, and plasma cells are nonreactive
  • MPO is not observed in the neoplastic cells of a wide variety of epithelial tumors and sarcomas
  • MPO is useful in differentiating between myeloid and lymphoid leukemias
  • Host Species: Rabbit Isotype: IgG Species Reactivity: Human, Mouse and Rat
  • Others not known
  • Epitope: Not determined Immunogen: Purified human granulocytic MPO Positive Control: Tonsil or spleen Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin)