RB9406P1
Epredia™ Lab Vision™ Pax-5 Rabbit Polyclonal Antibody with BSA and azide
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
PAX-5
Classification
Polyclonal
Conjugate
Unconjugated
Immunogen
Synthetic peptide derived from C-terminus of human Pax-5 protein
Regulatory Status
IVD
Primary or Secondary
Primary
Form
Concentrated
Applications
Western Blot
Concentration
200µg/mL
Host Species
Rabbit
Quantity
500 μL
Research Discipline
B-Cell
Target Species
Human, Mouse
Related Products
Description
- Description PAX-5 is a B cell specific activator protein (BSAP)
- In the early stages of B cell developmemt, PAX-5 influences the expression of several B-cell-specific genes, such as CD19 and CD20
- PAX-5 is expressed primarily inpro-, pre-, and mature B cells, but not in plasma cells
- Interestingly, PAX-5 mRNA is transiently detected in the mesencephalon and spinal cord during embryogenesis
- Expression then shifts to the fetal liver and correlates with the onset of B lymphopoiesis
- This indicates that PAX-5 is important in B cell development, but may also have a role in proper neuronal development
- Host Species: Rabbit Species Reactivity: Human, Mouse, Rat
- Others not tested
- Epitope: C-terminal Immunogen: Synthetic peptide derived from C-terminus of human PAX-5 protein Molecular Weight: 50kDa Positive Control: Tonsil, Raji cells Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting