Epredia™ Lab Vision™ Prostate Specific Antigen (PSA), Rabbit Monoclonal Antibody

Description

• PSA is a chymotrypsin-like serine protease (kallikrein family) produced by the prostate epithelium, and abundant in seminal fluid
• PSA can be detected in the sera of patients with prostatic carcinoma
• It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT)
• A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia
• PSA is used to confirm prostatic acinar cell origin in primary and metastatic carcinoma and to rule out non-prostatic carcinoma mimics
• Host Species: Rabbit Clone: EP1588Y Species Reactivity: Human
• Others not known
• Immunogen: A synthetic peptide corresponding to residues near the C-terminus of human PSA Molecular Weight: 34kDa Positive Control: Normal prostate or prostate carcinoma Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin)