RM2109S0

Epredia™ Lab Vision™ CD3ε Rabbit Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD3e

Classification

Monoclonal

Conjugate

Unconjugated

Immunogen

A synthetic peptide corresponding to residues in the cytoplasmic domain of human CD3epsilon. The antibody does not cross react with other subunits of CD3.

Regulatory Status

IVD

Primary or Secondary

Primary

Form

Concentrated

Applications

Immunohistochemistry (Paraffin)

Clone

EP449E

Host Species

Rabbit

Quantity

100 μL

Research Discipline

Cancer and Tumor Biology

Target Species

Human

Isotype

IgG

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Description

  • CD3 consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta)
  • The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR)
  • It is involved in signal transduction to the T cell interior following antigen recognition
  • CD3 antigen is a highly specific marker for T cells, and is present in the majority of T cell neoplasms
  • Host Species: Rabbit Clone: EP449E Isotype: IgG Species Reactivity: Human
  • Others not known
  • Immunogen: A synthetic peptide corresponding to residues in the cytoplasmic domain of human CD3ε
  • The antibody does not cross react with other subunits of CD3
  • Molecular Weight: 23kDa Positive Control: Tonsil Cellular Localization: Membrane Recommended for: Immunohistochemistry (Formalin/paraffin)