RM9116R1
Epredia™ Lab Vision™ CD8 Rabbit Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD8
Classification
Monoclonal
Conjugate
Unconjugated
Immunogen
Synthetic peptide sequence comprising the 13 C-terminal amino acids of the cytoplasmic domain of alpha chain of the CD8 molecule
Regulatory Status
IVD
Primary or Secondary
Primary
Form
Prediluted
Applications
Immunohistochemistry (Paraffin)
Clone
SP16
Host Species
Rabbit
Quantity
1 mL
Research Discipline
T-Cell
Target Species
Human
Related Products
Description
- CD8 molecule consists of two chains, termed α and β chain, which are expressed as a disulphide-linked α/β heterdimer or as an α/α homodimer on T cell subset, thymocytes and NK cells
- The majority of CD8+ T cells express CD8 as α/β heterdimer
- CD8 functions as a coreceptor in concert with TCR for binding the MHC class I/peptide complex
- The HIV-2 envelope glycoprotein binds CD8 alpha chain (but not β chain)
- Host Species: Rabbit Clone: SP16 Species Reactivity: Human
- Others not tested
- Epitope: C-terminus Immunogen: Synthetic peptide sequence comprising the 13 C-terminal amino acids of the cytoplasmic domain of α-chain of the CD8 molecule Positive Control: Tonsil Cellular Localization: Membrane Recommended for: Immunohistochemistry (Formalin/paraffin)