RM9130R7
Epredia™ Lab Vision™ p504s/AMACR, Rabbit Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
p504s/AMACR
Classification
Monoclonal
Conjugate
Unconjugated
Immunogen
Human p504s/AMACR polypeptide
Regulatory Status
ASR
Primary or Secondary
Primary
Form
Prediluted
Applications
Immunohistochemistry (Paraffin)
Clone
13H4
Host Species
Rabbit
Quantity
7 mL
Research Discipline
Cancer and Tumor Biology
Target Species
Human
Isotype
IgG
Related Products
Description
- Alpha methylacyl-CoA-racemase (AMACR), also known as p504s is an enzyme involved in the metabolism of branched-chain fatty acids
- p504s is expressed in various normal tissues and carcinomas, while it is overexpressed over 30-fold in prostate carcinoma compared to benign glandular tissues 1
- When p504s is overexpressed in atypical glands without basal cells, it establishes a diagnosis of prostatic carcinoma
- High-grade prostatic intraepithelial neoplasia, atypical adenomatous hyperplasia and urothelial carcinoma may also express p504s
- Host Species: Rabbit Clone: 13H4 Isotype: IgG Species Reactivity: Human
- Others not tested
- Immunogen: Human p504s/AMACR polypeptide Molecular Weight: ∽45 kDa Positive Control: Prostate carcinoma Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin)