ST1558100UG
MilliporeSigma™ anti-ALOX12 Clone: 2D10,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ST1558100UG-Each-of-1 | In Stock | ₹ 48,229.10 |
ST1558100UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,229.10
GST (18%): ₹ 8,681.238
Total Price: ₹ 56,910.338
Antigen
ALOX12
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Applications
ELISA, Immunoblot, Immunoblot
Clone
2D10
Formulation
In PBS, pH 7.2.
Immunogen
A recombinant polypeptide corresponding to amino acids 564-664 of human ALOX12, expressed as a GST fusion protein
Regulatory Status
RUO
Test Specificity
Recognizes the ALOX12 protein.
Content And Storage
−20°C
Isotype
IgG2a
Related Products
Description
- Specifically detects ALOX12 Clone: 2D10 in Human samples, and it is validated for ELISA, Immuno Blotting Lipoxygenases (LOXs) are a family of non-heme iron dioxygenases that are involved in the production and metabolism of fatty acid hydroperoxidases
- There are six lipoxygenase isozymes; 5-LOX, 12R-LOX, 12S-LOX, 15-LOX-1 and 15-LOX-2, which catalyze the regio-selective addition of oxygen into arachidonic acid, and epidermal LOX (E-LOX) which metabolizes 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE) to a specific epoxyalcohol compound
- Different isozymes have different physiological roles; 5-, 12R-, 12S- and 15-LOX-1 have proliferative, antiapoptotic and angiogenic functions whilst 15-LOX-2 has roles in differentiation, growth arrest and the induction of apoptosis
- E-LOX, the most divergent member of this family, is involved in terminal differentiation of keratinocytes and has a major role in skin barrier function
- Perturbations in lipoxygenase enzymes have been implicated in various human diseases including bronchial asthma, atherosclerosis, osteoporosis and some cancers.