343536

1-Boc-piperazine

97%

Manufacturer: Sigma Aldrich

CAS Number: 57260-71-6

Synonym(S): tert-Butyl piperazine-1-carboxylate

Select a Size

Pack Size SKU Availability Price
1 G 343536-1-G In Stock ₹ 2,575.20
5 G 343536-5-G In Stock ₹ 11,155.50
25 G 343536-25-G In Stock ₹ 19,580.40

343536 - 1 G

₹ 2,575.20

In Stock

Quantity

1

Base Price: ₹ 2,575.20

GST (18%): ₹ 463.536

Total Price: ₹ 3,038.736

Quality Level

200

Assay

97%

form

solid

mp

43-47 °C (lit.)

SMILES string

CC(C)(C)OC(=O)N1CCNCC1

InChI

1S/C9H18N2O2/c1-9(2,3)13-8(12)11-6-4-10-5-7-11/h10H,4-7H2,1-3H3

InChI key

CWXPZXBSDSIRCS-UHFFFAOYSA-N

Other Options

Image Product Name Manufacturer Price Range
Tert-Butyl 1-Piperazinecarboxylate
-- ₹ 267.00 - ₹ 81,702.00
N-Boc-piperazine
-- ₹ 1,246.00 - ₹ 11,303.00
57260-71-6 | t-Butyl piperazine-1-carboxylate
-- ₹ 267.00 - ₹ 8,722.00

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Description

  • General description: 1-Boc-piperazine is an N-Boc protected piperazine. Crosscoupling of 1-Boc-piperazine with aryl iodides using CuBr/1,1′-bi-2-naphthol (catalyst) and K3PO4 (base) has been reported.[1] 1-Boc-piperazine undergoes Buchwald-Hartwig coupling reactions with aryl halides.[2] 1-Boc-piperazine can be prepared in 80% yield via solvent-free N-Boc protection catalyzed by iodine.[3]
  • Application: 1-Boc-piperazine may be used in:preparation of series of (m-phenoxy)phenyl substituted piperazine derivatives[4]termination step during synthesis of α,β-poly(2-oxazoline) lipopolymers via living cationic ring opening polymerization[5]preparation of monosubstituted piperazines, e.g. in the synthesis of indazole DNA gyrase inhibitors[6]

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves