42-033-65MG

MilliporeSigma™ Calbiochem™ KB-R7943

Manufacturer: MilliporeSigma™

CAS Number: 182004-65-5

Select a Size

Pack Size SKU Availability Price
Each of 1 42-033-65MG-Each-of-1 In Stock ₹ 17,024.81

42-033-65MG - Each of 1

₹ 17,024.81

In Stock

Quantity

1

Base Price: ₹ 17,024.81

GST (18%): ₹ 3,064.466

Total Price: ₹ 20,089.276

Color

White

Target Proteins

Na+/Ca2+ exchangers

Molecular Formula

C16H17N3O3S·MeSO3H

Solubility

DMSO or H2O

Form

Crystalline Solid

Description

98% by HPLC

CAS

182004-65-5

Formula Weight

427.5g/mol

Content And Storage

Hygroscopic, Protect from light

Quantity

5 mg

Other Options

Image Product Name Manufacturer Price Range
eMolecules​ Medchem Express / KB-R7943 (mesylate) / 10mg / 446265594 / HY-15415 / / 182004-65-5 / MFCD00952138 / 427.490 / C17H21N3O6S2
-- ₹ 14,672.54
CARBAMIMIDOTHIOIC ACID, 2-[4-[(4-NITROPHENYL)METHOXY]PHENYL]ETHYL ESTER, METHANESULFONATE (1:1)
-- ₹ 8,366.00 - ₹ 25,721.00
KB-R7943 (mesylate)
-- ₹ 6,408.00 - ₹ 35,244.00
182004-65-5 | Kb-r7943 mesylate
-- ₹ 4,005.00 - ₹ 10,413.00

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Description

  • A cell-permeable isothiourea derivative that inhibits the influx/reverse mode of Na + /Ca 2+ exchangers (NCX; IC 50 = 4.3μM, 4.7μM, and 1.4μM for NCX1,NCX2, and NCX3, respectively) and directly modulates Na + /Mg 2+ exchange in a Ca 2+ -dependent manner
  • Reported to offer neuronal and cardioprotection
  • Also inhibits nicotinic acetylcholine receptors and NMDA receptor channels (IC 50 < 10μM).