4783549

Tocris Bioscience™ Kainic acid

Kainate agonist; excitant and neurotoxin

Manufacturer: Fischer Scientific

CAS Number: 487-79-6

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Chemical Name or Material

(2 S,3 S,4 S)-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid

Assay Percent Range

>98%

Molecular Formula

C10H15NO4

Purity

98%

CAS

487-79-6

Target

Kainate Receptor Agonists

Formula Weight

Observed MW: 213.23

Other Options

Image Product Name Manufacturer Price Range
Tocris Bioscience™ Kainic acid
-- --
Tocris Bioscience™ Kainic acid
-- --
Tocris Bioscience™ Kainic acid
-- --
Enzo Life Sciences Kainic acid (25mg). CAS: 487-79-6
-- ₹ 43,949.09
Enzo Life Sciences Kainic acid (5mg). CAS: 487-79-6
-- ₹ 9,211.50
MilliporeSigma™ Calbiochem™ Kainic Acid
-- ₹ 32,858.80
Medchemexpress LLC HY-N2309 1mg Medchemexpress, Kainic acid CAS:487-79-6 Purity:>98%
-- --
Apexbio Technology LLC glatiramer acetate 25mg. 487-79-6. MFCD00077806
-- ₹ 24,920.00
Kainic acid
-- ₹ 6,230.00 - ₹ 80,990.00
487-79-6 | 3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2S,3S,4S)-
-- ₹ 13,172.00 - ₹ 37,736.00

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Description

  • Kainic acid, also known as kainate, is a selective agonist of kainate ionotropic glutamate receptors (EC50 = 0.6 - 7.4 μM) and a partial agonist at AMPA receptors (EC50 = 31 μM - 170 μM)
  • Kainic acid is used to model epilepsy in vivo and to study the mechanisms of neurodegeneration and neurocytosis induced by excess stimulation by kainic acid
  • Kainate is shown to be involved in amyloidogenic processing of amyloid precursor protein and Aβ peptides in Alzheimer's disease
  • Related compounds include synthetic Kainic acid (Cat
  • No
  • 7065), the kainate receptor agonist Domoic acid (Cat
  • No
  • 0269) and the antagonist NBQX (Cat
  • No
  • 0373).

SAFETY INFORMATION

  • Recommended Storage : Store at Room Temperature