69-941-00
Tocris™ HODHBt
Manufacturer: Tocris™
CAS Number: 28230-32-2
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Chemical Name or Material
3-Hydroxy-1,2,3-benzotriazin-4(3 H)-one
Quantity
100 mg
Target
Antiviral Compounds
Formula Weight
163.14
Purity
98%
CAS
28230-32-2
Solubility
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Molecular Formula
C7H5N3O2
Product Type
Inhibitor
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
eMolecules AstaTech / 3-HYDROXYBENZO[D][123]TRIAZIN-4(3H)-ONE / 1g / 721956865 / O11014 / 95.000 / 28230-32-2 / MFCD00042803 / 163.136 / C7H5N3O2 | -- | ₹ 6,026.19 | ||
HODHBt | -- | ₹ 4,450.00 | ||
28230-32-2 | 3-Hydroxy-1,2,3-ben zotriazin-4(3H)-one | -- | ₹ 3,293.00 - ₹ 20,381.00 |
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Description
- HODHBt is a STAT5-SUMO protein-protein interaction inhibitor
- Blocks SUMOylation of phosphorylated STAT5
- Reactivates latent HIV-1 reservoir in central memory T cells (TCM)
- Increases viral release by ~2.7-fold at a concentration of 100 μM in combination with IL-2 compared to unstimulated cells; reduces size of latent HIV-1 reservoir in vitro .
SAFETY INFORMATION
- Recommended Storage : Store at -20°C