7114671
Tocris Bioscience™ Pomalidomide
Cereblon binder; also TNF-α inhibitor and antiangiogenic
Manufacturer: Fischer Scientific
CAS Number: 19171-19-8
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Chemical Name or Material
4-Amino-2-(2,6-dioxo-3-piperidinyl)-1 H-isoindole-1,3(2 H)-dione
Assay Percent Range
>98%
Molecular Formula
C13H11N3O4
Purity
98%
CAS
19171-19-8
Target
Ubiquitin Ligase (E3) Inhibitors
Formula Weight
Observed MW: 273.24
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ Pomalidomide | -- | ₹ 19,847.00 | ||
Tocris Bioscience™ Pomalidomide | -- | ₹ 81,969.00 | ||
Medchemexpress LLC HY-10984 1g , Pomalidomide CAS:19171-19-8 Purity:>98% | -- | ₹ 18,503.10 | ||
Medchemexpress LLC HY-10984 500mg , Pomalidomide CAS:19171-19-8 Purity:>98% | -- | ₹ 14,391.30 | ||
eMolecules Pomalidomide | 19171-19-8 | MFCD12756407 | 5g | -- | ₹ 3,151.49 | ||
Ubpbio A ligand of Cereblon (CRBN), the substrate receptor of the CUL4CRBN E3 ubiquitin ligase, CAS# 19171-19-8, >98% purity | -- | ₹ 6,141.00 | ||
Ubpbio A ligand of Cereblon (CRBN), the substrate receptor of the CUL4CRBN E3 ubiquitin ligase, CAS# 19171-19-8, >98% purity | -- | ₹ 17,399.50 | ||
Medchemexpress LLC HY-10984 50mg Medchemexpress, Pomalidomide CAS:19171-19-8 Purity:>98% | -- | ₹ 8,597.40 | ||
Sigma Aldrich Fine Chemicals Biosciences Pomalidomide | 19171-19-8 | MFCD12756407 | 5mg | -- | ₹ 16,463.22 | ||
Medchemexpress LLC HY-10984 200mg , Pomalidomide CC-4047 CAS:19171-19-8 Purity:98% | -- | ₹ 12,335.40 |
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Description
- Potent TNF-α inhibitor (IC50 = 13 nM)
- Also potently inhibits IL-2 (EC50 = 8 nM)
- Thalidomide derivative
- Binds cereblon and inhibits its ubiquitination
- Exhibits antiproliferative effects in a Namalwa lymphoma cell line
- Antiangiogenic
- Promotes degradation of transcription factor SALL4.
SAFETY INFORMATION
- Recommended Storage : Store at 4°C