7116034
Clofarabine
Deoxycytidine kinase (dCK) substrate
Manufacturer: Fischer Scientific
CAS Number: 123318-82-1
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Chemical Name or Material
2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purin-6-amine
Assay Percent Range
>99%
Formula Weight
Observed MW: 303.68
CAS
123318-82-1
Molecular Formula
C10H11ClFN5O3
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
eMolecules Medchem Express / Clofarabine / 10mg / 446271656 / HY-A0005 / / 123318-82-1 / [null] / 303.680 / C10H11ClFN5O3 | -- | ₹ 9,563.94 | ||
Sigma Aldrich Fine Chemicals Biosciences Clofarabine >=98% (HPLC) | 123318-82-1 | MFCD00871077 | 25MG | -- | ₹ 57,031.20 | ||
eMolecules Ambeed / (2R3R4S5R)-5-(6-Amino-2-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol / 1mg / 761012491 / A195550 / / 123318-82-1 / MFCD00871077 / 303.680 / C10H11ClFN5O3 | -- | ₹ 2,148.46 | ||
Clofarabine | -- | ₹ 55,233.40 | ||
Clofarabine | -- | ₹ 14,763.32 | ||
Selleck Chemical LLC Clofarabine 10mg 123318-82-1 | -- | ₹ 15,699.60 | ||
Selleck Chemical LLC Clofarabine 50mg 123318-82-1 | -- | ₹ 39,516.00 | ||
Clofarabine | -- | ₹ 1,46,613.80 | ||
Clofarabine System Suitability Mixture | -- | ₹ 1,37,098.63 | ||
9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)- | -- | ₹ 890.00 - ₹ 48,950.00 |
Related Products
Description
- Deoxycytidine kinase (dCK) substrate
- Phosphorylated to form clofarabine triphosphate, which competes with dATP for DNA polymerase-α and -ε and potently inhibits ribonucleotide reductase (IC50 = 65 nM)
- Induces apoptosis by directly altering mitochondrial transmembrane potential
- Demonstrates growth inhibition and cytotoxic activity in a variety of leukemias and solid tumors.
SAFETY INFORMATION
- Recommended Storage : Store at 4°C