7139256
A 485
Histone Acetyltransferase Inhibitors
Manufacturer: Fischer Scientific
CAS Number: 1889279-16-6
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CAS
1889279-16-6
Molecular Formula
C25H24F4N4O5
Purity
98%
Synonym
(1R)-N-[(4-Fluorophenyl)methyl]-2,3-dihydro-5-[[(methylamino)carbonyl]amino]-2′,4′-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[1H-indene-1,5′-oxazolidine]-3′-acetamide
Formula Weight
536.48
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
A 485 | -- | ₹ 32,040.00 | ||
A 485 | -- | ₹ 1,24,956.00 | ||
Medchemexpress LLC HY-107455 100mg , A-485 CAS:1889279-16-6 Purity:>98% | -- | ₹ 87,843.00 | ||
Medchemexpress LLC HY-107455 50mg , A-485 CAS:1889279-16-6 Purity:>98% | -- | ₹ 50,930.25 | ||
Selleck Chemical LLC A-485 2mg 1889279-16-6 | -- | ₹ 21,039.60 | ||
Medchemexpress LLC A-485 | 1889279-16-6 | MFCD31619258 | 5 mg | -- | ₹ 21,026.25 | ||
A-485 | -- | ₹ 19,409.23 - ₹ 78,318.88 | ||
A-485 | -- | ₹ 9,790.00 - ₹ 83,660.00 | ||
1889279-16-6 | (1R)-N-[(4-Fluorophenyl)methyl]-2,3-dihydro-5-[[(methylamino)carbonyl]amino]-2',4'-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[1H-indene-1,5'-oxazolidine]-3'-acetamide | -- | ₹ 4,005.00 - ₹ 66,394.00 |
Related Products
Description
- Potent and selective p300/CREB-binding protein (CBP) HAT domain inhibitor (IC50 values are 2.6 and 9.8 nM for the CBP-bromodomain HAT-C/H3 (BHC) and p300-BHC domains, respectively)
- Displays > 1000-fold selectivity over closely related HATs
- Suppresses proliferation in several hematological malignancies and AR+ prostate cancer cell lines in vitro
- Inhibits tumor growth in a castration-resistant prostate cancer xenograft model
- Orally bioavailable
- To request the negative control for A 485, please fill out the A 486 request form on the SGC website.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C