75-901-0
Tocris Bioscience™ Pexidartinib
Manufacturer: Fischer Scientific
CAS Number: 1029044-16-3
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 75-901-0-Each-of-1 | In Stock | ₹ 14,079.80 |
75-901-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 14,079.80
GST (18%): ₹ 2,534.364
Total Price: ₹ 16,614.164
Chemical Name or Material
N-[5-[(5-Chloro-1 H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)-3-pyridinemethanamine
Quantity
10 mg
Molecular Formula
C20H15ClF3N5
CAS
1029044-16-3
Target
Additional RTK Inhibitors
Purity
98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ Pexidartinib | -- | -- | ||
Tocris Bioscience™ Pexidartinib | -- | ₹ 58,829.00 | ||
Medchemexpress LLC HY-16749 10g , Pexidartinib CAS:1029044-16-3 Purity:>98% | -- | ₹ 3,59,782.50 | ||
Medchemexpress LLC HY-16749 1g , Pexidartinib CAS:1029044-16-3 Purity:>98% | -- | ₹ 70,087.50 | ||
Medchemexpress LLC HY-16749 500mg , Pexidartinib CAS:1029044-16-3 Purity:>98% | -- | ₹ 42,052.50 | ||
Selleck Chemical LLC Pexidartinib (PLX3397) 10mg 1029044-16-3 | -- | ₹ 21,039.60 | ||
Medkoo Biosciences Inc Pexidartinib | 1029044-16-3 | MFCD28900745 | 200mg | -- | ₹ 27,256.25 | ||
Medchemexpress LLC HY-16749 50mg , Pexidartinib CAS:1029044-16-3 Purity:>98% | -- | ₹ 14,017.50 | ||
Medchemexpress LLC HY-16749 200mg , Pexidartinib PLX-3397 CAS:1029044-16-3 Purity:98% | -- | ₹ 24,297.00 | ||
Medchemexpress LLC HY-16749 100mg Medchemexpress, Pexidartinib CAS:1029044-16-3 Purity:>98% | -- | ₹ 17,755.50 |
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Description
- Pexidartinib is a potent colony-stimulating factor-1 receptor (CSF-1R) tyrosine kinase inhibitor (IC50 = 20 nM)
- In the B16F10 mouse melanoma model, Pexidartinib reduces the systemic and local accumulation of macrophages without affecting Gr-1+ myeloid derived suppressor cells
- When combined with tumor-specific CD8 T cell immunotherapy, Pexidartinib promotes the control of tumor growth
- In the BRAFV600E-driven mouse melanoma model, Pexidartinib improves the efficacy of adoptive cell therapy with reduction of TIMs and an increase in tumor-infiltrating lymphocytes and T cells
- Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C