76-311-0
Tocris Bioscience™ Idelalisib
Manufacturer: Fischer Scientific
CAS Number: 870281-82-6
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 76-311-0-Each-of-1 | In Stock | ₹ 7,716.30 |
76-311-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 7,716.30
GST (18%): ₹ 1,388.934
Total Price: ₹ 9,105.234
Chemical Name or Material
5-Fluoro-3-phenyl-2-[(1 S)-1-(9 H-purin-6-ylamino)propyl]-4(3 H)-quinazolinone
Quantity
10 mg
Molecular Formula
C22H18FN7O
CAS
870281-82-6
Target
PI 3-Kinase Inhibitors
Purity
98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ Idelalisib | -- | -- | ||
Tocris Bioscience™ Idelalisib | -- | ₹ 32,040.00 | ||
Apexbio Technology LLC CAL-101 (Idelalisib, GS-1101), 20mg. Cas: 870281-82-6 MFCD: MFCD19443647. PI3K inhibitor | -- | ₹ 7,565.00 | ||
Enzo Life Sciences Idelalisib (free base) (25mg). CAS: 870281-82-6 | -- | ₹ 20,572.35 | ||
Selleck Chemical LLC Idelalisib (CAL-101, GS-1101) 10mg 870281-82-6 | -- | ₹ 15,699.60 | ||
Selleck Chemical LLC Idelalisib (CAL-101, GS-1101) 50mg 870281-82-6 | -- | ₹ 49,359.40 | ||
Apexbio Technology LLC CAL-101 (Idelalisib, GS-1101), 5mg. Cas: 870281-82-6 MFCD: MFCD19443647. PI3K inhibitor | -- | ₹ 4,717.00 | ||
Cayman Chemical CAL-101, 870281-82-6, 5 mg | -- | ₹ 3,951.60 | ||
Selleck Chemical LLC Idelalisib (CAL-101, GS-1101) 10mM/1mL 870281-82-6 | -- | ₹ 21,039.60 | ||
Enzo Life Sciences Idelalisib (free base) (100mg). CAS: 870281-82-6 | -- | ₹ 53,603.81 |
Related Products
Description
- Idelalisib is a potent PI 3-Kinase δ inhibitor (IC50 = 2.5 nM for p110δ); it exhibits >40-fold selectivity for the δ isoform over other PI 3-K class I enzymes (IC50s = 89, 565, and 820 nM for p110γ, p110β, and p110α respectively)
- Idelalisib blocks constitutive PI 3-K signaling in malignant B-cell lines and primary patient tumor cells
- Idelalisib inhibits chronic lymphocytic leukemia cell chemotaxis and downregulates chemokine secretion triggered by B-cell receptor signaling in stromal cocultures
- Idelalisib lacks significant cytotoxicity toward natural killer (NK) cells
- Idelalisib also decreases production of inflammatory cytokines, including TNF-γ, CD40L, and IL-6 by T cells and IFN-γ by NK cells
- Idelalisib is cell-permeable and orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C