930598

VH032-OH

≥95%

Manufacturer: Sigma Aldrich

CAS Number: 2244684-42-0

Synonym(S): (2S,4R)-1-((S)-2-Acetamido-3,3-dimethylbutanoyl)-4-hydroxy-N-[2-hydroxy-4-(4-methylthiazol-5-yl)benzyl]pyrrolidine-2-carboxamide, L-Prolinamide, N-acetyl-3-methyl-L-valyl-4-hydroxy-N-[[2-hydroxy-4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-

Select a Size

Pack Size SKU Availability Price
50 MG 930598-50-MG In Stock ₹ 20,490.00

930598 - 50 MG

₹ 20,490.00

In Stock

Quantity

1

Base Price: ₹ 20,490.00

GST (18%): ₹ 3,688.20

Total Price: ₹ 24,178.20

ligand

VH032

Quality Level

100

Assay

≥95%

form

powder

reaction suitability

reagent type: ligand

functional group

hydroxyl

storage temp.

2-8°C

Other Options

Image Product Name Manufacturer Price Range
eMolecules​ Medchem Express / VH032-OH / 25mg / 686921804 / HY-136164 / / 2244684-42-0 / [null] / 488.600 / C24H32N4O5S
-- ₹ 51,491.84
VH 032, phenol
-- ₹ 10,235.00 - ₹ 1,34,568.00
VH032-OH
-- ₹ 10,947.00 - ₹ 1,38,484.00

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Description

  • Application: VH032-OH is a functionalized von-Hippel-Lindau (VHL) ligand with a terminal hydroxyl group. Allows rapid conjugation with many linkers containing active leaving groups. A basic building block for development of a protein degrader library.Technology Spotlight: Degrader Building Blocks for Targeted Protein DegradationProtein Degrader Building Blocks
  • Other Notes: Targeted Protein Degradation by Small Molecules Destruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERGSmall-Molecule PROTACS: New Approaches to Protein DegradationTargeted Protein Degradation: from Chemical Biology to Drug DiscoveryImpact of linker length on the activity of PROTACs
  • Legal Information: PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable