Methotrexate solution
1.0 mg/mL in methanol with 0.1N NaOH, ampule of 1 mL, certified reference material, Cerilliant®
Manufacturer: Supelco
CAS Number: 59-05-2
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 ML | M-136-1-ML | In Stock | ₹ 10,068.10 |
M-136 - 1 ML
In Stock
Quantity
1
Base Price: ₹ 10,068.10
GST (18%): ₹ 1,812.258
Total Price: ₹ 11,880.358
grade
certified reference material
Quality Level
300
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in methanol with 0.1N NaOH
technique(s)
gas chromatography (GC): suitableliquid chromatography (LC): suitable
application(s)
pharmaceutical (small molecule)
format
single component solution
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Indofine Chemical METHOTREXATE, Products for Life Science, 59-05-2, 100 mg | -- | ₹ 6,652.75 | ||
Medchemexpress LLC HY-14519 500mg , Methotrexate CAS:59-05-2 Purity:>98% | -- | ₹ 16,073.40 | ||
MilliporeSigma™ Calbiochem™ Methotrexate | -- | ₹ 12,217.92 | ||
Selleck Chemical LLC Methotrexate 100mg 59-05-2 NCI-C04671 | -- | ₹ 15,699.60 | ||
Sigma Aldrich Fine Chemicals Biosciences Methotrexate United States Pharmacopeia (USP) Reference Standard | 59-05-2 | MFCD00064370 | 500MG | -- | ₹ 47,632.80 | ||
Cayman Chemical Methotrexate, 59-05-2, 100 mg | -- | ₹ 4,806.00 | ||
Selleck Chemical LLC Methotrexate 10mM/1mL 59-05-2 NCI-C04671 | -- | ₹ 21,039.60 | ||
Methotrexate | -- | ₹ 12,165.60 | ||
Methotrexate | -- | ₹ 41,791.50 | ||
Methotrexate | -- | ₹ 16,516.80 |
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Description
- General description: A Certified Spiking Solution® for use in therapeutic drug monitoring (TDM) analyses by HPLC or LC/MS. Used in the treatment of cancer and autoimmune diseases, methotrexate is an antimetabolite and antifolate drug monitored by clinical labs to ensure patients remain within the drug′s therapeutic range. The Snap-N-Spike® format allows laboratories to eliminate weighing operations of hazardous substances such as methotrexate, significantly reducing occupational exposure hazards related to handling of acutely toxic powders, and provides the ability to spike into their matrix of choice just before use.
- Application: Pharmacokinetic analysis: Methotrexate solution is employed in advanced pharmacokinetic studies using UV-Vis spectrophotometric and colorimetric methods. This application facilitates precise quantification in plasma and tissue, crucial for evaluating drug distribution and effectiveness in cancer treatments (Febrianti et al., 2024).Toxicity and safety monitoring: Observational studies utilize Methotrexate solution to investigate root causes of medication errors and manage toxicity in elderly patients. This research supports safer clinical practices by identifying risk factors and improving patient safety protocols (Bisht et al., 2024).Nephrotoxicity prevention: Research on Methotrexate solution examines hydration strategies to mitigate nephrotoxicity, enhancing therapeutic outcomes. This study is pivotal in optimizing Methotrexate use in clinical settings, ensuring higher safety and efficacy for patients undergoing chemotherapy (Hasanpour et al., 2024).
- Legal Information: CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - Met. Corr. 1 - STOT SE 1
Target Organs
Eyes,Central nervous system
WGK
WGK 2
Flash Point(F)
closed cup
Flash Point(C)
closed cup