PHR1353

Estradiol

Pharmaceutical Secondary Standard; Certified Reference Material

Manufacturer: Supelco

CAS Number: 50-28-2

Synonym(S): β-Estradiol, 1,3,5-Estratriene-3,17β-diol, 17β-Estradiol, 3,17β-Dihydroxy-1,3,5(10)-estratriene, Dihydrofolliculin

Select a Size

Pack Size SKU Availability Price
1 G PHR1353-1-G In Stock ₹ 13,899.30

PHR1353 - 1 G

₹ 13,899.30

In Stock

Quantity

1

Base Price: ₹ 13,899.30

GST (18%): ₹ 2,501.874

Total Price: ₹ 16,401.174

grade

certified reference materialpharmaceutical secondary standard

Quality Level

300

Agency

traceable to BP 729traceable to Ph. Eur. E1620000traceable to USP 1250008

API family

estradiol

CofA

current certificate can be downloaded

technique(s)

HPLC: suitablegas chromatography (GC): suitable

mp

176-180 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

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Description

  • General description: Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.Estradiol is a steroid hormone present naturally in the human body. The availability of this hormone is quintessential in older women as it is a determinant of menopausal syndromes. It is utilized for the prevention of cardiovascular diseases.[1]
  • Application: Estradiol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.[2][1][3][4]
  • Biochem/physiol Actions: The major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female phenotype in embryogenesis and during puberty by regulating gene transcription and, thus, protein synthesis. It also induces the production of gonadotropins which, in turn, induce ovulation. Exposure to estradiol increases breast cancer incidence and proliferation.
  • Analysis Note: These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
  • Other Notes: This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
  • Footnote: To see an example of a Certificate of Analysis for this material enter LRAC3704 in the slot below. This is an example certificate only and may not be the lot that you receive.
  • Recommended products: Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

SAFETY INFORMATION

Pictograms

GHS08,GHS09

Signal Word

Danger

Hazard Statements

H351,H360FD,H362,H410

Precautionary Statements

P202 - P260 - P263 - P264 - P273 - P308 + P313

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Lact. - Repr. 1A

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable