Methotrexate
Pharmaceutical Secondary Standard; Certified Reference Material
Manufacturer: Supelco
CAS Number: 59-05-2
Synonym(S): Methotrexate, (+)-Amethopterin, 4-Amino-10-methylfolic acid, 4-Amino-N10-methylpteroyl-L-glutamic acid, Antifolan, MTX, Methylaminopterin
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 G | PHR1396-1-G | In Stock | ₹ 12,165.60 |
PHR1396 - 1 G
In Stock
Quantity
1
Base Price: ₹ 12,165.60
GST (18%): ₹ 2,189.808
Total Price: ₹ 14,355.408
grade
certified reference materialpharmaceutical secondary standard
Quality Level
300
Agency
traceable to Ph. Eur. M1000000traceable to USP 1414003
API family
methotrexate
CofA
current certificate can be downloaded
technique(s)
HPLC: suitablegas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Indofine Chemical METHOTREXATE, Products for Life Science, 59-05-2, 100 mg | -- | ₹ 6,652.75 | ||
Medchemexpress LLC HY-14519 500mg , Methotrexate CAS:59-05-2 Purity:>98% | -- | ₹ 16,073.40 | ||
MilliporeSigma™ Calbiochem™ Methotrexate | -- | ₹ 12,217.92 | ||
Selleck Chemical LLC Methotrexate 100mg 59-05-2 NCI-C04671 | -- | ₹ 15,699.60 | ||
Sigma Aldrich Fine Chemicals Biosciences Methotrexate United States Pharmacopeia (USP) Reference Standard | 59-05-2 | MFCD00064370 | 500MG | -- | ₹ 47,632.80 | ||
Cayman Chemical Methotrexate, 59-05-2, 100 mg | -- | ₹ 4,806.00 | ||
Selleck Chemical LLC Methotrexate 10mM/1mL 59-05-2 NCI-C04671 | -- | ₹ 21,039.60 | ||
Methotrexate solution | -- | ₹ 10,068.10 | ||
Methotrexate | -- | ₹ 41,791.50 | ||
Methotrexate | -- | ₹ 16,516.80 |
Related Products
Description
- General description: Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.Methotrexate is an antagonist of folic acid that inhibits dihydrofolate reductase (DHFR) enzyme, reversibly and results in impaired DNA synthesis and cellular replication.[1] Methotrexate has been used in treatment of rheumatoid arthritis[2] and also for maintenance therapy in childhood acute lymphocytic leukemia (ALL).[3]
- Application: Methotrexate may be used as a pharmaceutical secondary reference standard for the determination of the analyte in plasma samples[4] and pharmaceutical formulations[5] by various techniques.
- Analysis Note: These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
- Other Notes: This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
- Footnote: To see an example of a Certificate of Analysis for this material enter LRAB9958 in the slot below. This is an example certificate only and may not be the lot that you receive.
- Recommended products: Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral - Muta. 2 - Repr. 1B - STOT RE 1
Target Organs
Liver,Bone marrow
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable