Y0001596

Diacerein impurity B

European Pharmacopoeia (EP) Reference Standard

Manufacturer: Sigma Aldrich

CAS Number: 481-72-1

Synonym(S): Aloe-emodin, 1,8-Dihydroxy 3-hydroxymethylanthraquinone, 1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone, 3-Hydroxymethylchrysazine, Rhabarberone

Select a Size

Pack Size SKU Availability Price
20 MG Y0001596-20-MG In Stock ₹ 14,267.35

Y0001596 - 20 MG

₹ 14,267.35

In Stock

Quantity

1

Base Price: ₹ 14,267.35

GST (18%): ₹ 2,568.123

Total Price: ₹ 16,835.473

biological source

synthetic

grade

pharmaceutical primary standard

Agency

EP

API family

diacerein

form

solid

manufacturer/tradename

EDQM

technique(s)

gas chromatography (GC): suitableliquid chromatography (LC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Other Options

Image Product Name Manufacturer Price Range
Medchemexpress LLC HY-N0189 100mg Medchemexpress, Aloe emodin CAS:481-72-1 Purity:>98%
-- ₹ 9,158.10
Aloe-emodin, ≥97% (HPLC), MilliporeSigma™ Supelco™
-- ₹ 44,678.00
Sigma Aldrich Fine Chemicals Biosciences Aloe-emodin >=95% (HPLC) | 481-72-1 | MFCD00017373 | 25MG
-- ₹ 1,09,220.80
eMolecules​ Ambeed / 18-Dihydroxy-3-(hydroxymethyl)anthracene-910-dione / 25mg / 552579088 / A142364 / / 481-72-1 / MFCD00017373 / 270.240 / C15H10O5
-- ₹ 2,057.68
Aloe-emodin
-- ₹ 40,214.88
Aloe-emodin
-- ₹ 35,386.93
Aloe-emodin
-- ₹ 65,166.50
Aloe-emodin
-- ₹ 65,166.50
Aloe emodin
-- ₹ 1,513.00 - ₹ 50,641.00

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Description

  • General description: Diacerein is known to be a suitable drug to treat osteoarthritis and prevent vascular diseases. It is a semi-synthetic anthraquinone derivative which acts by inhibiting the production of interleukin-1 and secretion of metalloproteases.[1][2]
  • Application: Diacerein impurity B EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
  • Biochem/physiol Actions: Laxative/cathartic compound; increases the contraction of intestinal smooth muscle by releasing endogenous acetylcholine. Anti-tumor activity is associated with an increased production of reactive oxygen species (ROS) that, in turn, reduces the mitochondrial transmembrane electrical potential, thus inducing a permeability transition that sets in motion a series of events culminating in cellular apoptosis. Genotoxicity and mutagenicity appear to be due to the inhibition of topoisomerase II activity by aloe emodin.
  • Packaging: The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
  • Other Notes: Sales restrictions may apply.

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable