NBP226231

Novus Biologicals™ Imidazoquinoline Resiquimod (R-848), TLR7 and TLR8 Ligand

Manufacturer: Novus Biologicals™

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Buffer

DMSO

For Use With (Application)

Identity determined by MS, 1H-NMR and 13C-NMR. This product is useful for activation of mouse TLR7 and human TLR7 and TLR8. Stimulation of TLR8 has been achieved with 0.5-5 ug/mL. Use in functional assays reported in scientific literature (PMID 26134251).

Purity

>98%, by HPLC.

Content And Storage

Store at -20°C.

Product Type

Imidazoquinoline Resiquimod (R-848), TLR7 and TLR8 Ligand

Quantity

0.5 mg

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Description

  • Imidazoquinoline Resiquimod (R-848), TLR7 and TLR8 ligand is a low molecular weight synthetic molecule of the Imidazoquinoline family
  • It has potent immunostimulatory activity
  • It stimulates antibody secretion, cytokine production, protection from apoptosis and CD80 up-regulation
  • Species: Human Stimulation of TLR8 has been achieved with 0.5-5μg/mL Recommended Storage Store at 4°C short term
  • Aliquot and store at -20°C long term
  • Avoid freeze-thaw cycles.