78-971

Tocris Bioscience™ Sakura 6

Manufacturer: Tocris Bioscience™

CAS Number: 2490708-79-5

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Purity

95%

Content And Storage

Store at -20°C

Quantity

1 mg

CAS

2490708-79-5

Molecular Weight (g/mol)

M.W. (Observed): 599.73: 0.95

Description

  • Sakura 6 is a synthetic serotonin transporter (SERT)-binding peptide
  • Promotes interaction of SERT and neuronal nitric oxide synthase, reducing SERT activity and cell surface SERT, increases auto-inhibition, reduces synaptic 5-HT release and reduces firing in the dorsal raphe nucleus
  • Induces an acute depressive phenotype in a mouse model of depression.