PEP0869
Invitrogen™ Human Occludin Synthetic Peptide
Manufacturer: Invitrogen™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PEP0869-Each-of-1 | In Stock | ₹ 16,901.10 |
PEP0869 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,901.10
GST (18%): ₹ 3,042.198
Total Price: ₹ 19,943.298
Gene ID (Entrez)
100506658
Purification Method
purified
Common Name
Human Occludin
Content And Storage
-20°C
Format
Liquid
For Use With (Application)
Blocking Assay, Control
Lyophilized
No
Product Type
Peptide
Regulatory Status
RUO - research use only
Species
Human
Accession Number
Q16625
Concentration
200 μg/mL
Description
Synthetic Peptide
Formulation
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Gene Symbol
OCLN
Preservative
0.02% sodium azide
Quantity
50 μg
Storage Buffer
PBS
Related Products
Description
- OCLN Synthetic Peptide, PEP-0869, from Invitrogen
- Occludin is a 65 kDa protein that can exist in a variety of phosphorylated forms, ranging up to approximately 82 kDa
- Occludin is thought to be involved in regulating both the localization and the function of occludin
- Polyunsaturated fatty acids are known to up-regulate occludin expression, increasing the transendothelial cell resistance and reducing the cellular permeability to large molecules
- The level of occludin varies greatly depending on tissue; in brain tissue, occludin is highly and continuously expressed at cell-cell contact sites, whereas non-neural tissues show lower expression and discontinuous distribution
- Overall structural features of the occludin protein are highly conserved in all the species examined
- Under-expression of tight junction proteins, including occludin, is a key molecular abnormality responsible for the increased permeability of tumor endothelial tight junctions, which contributes to brain tumor edemas
- This peptide corresponds to 15 amino acids near the carboxy terminus of human OCLN.PEP-0869 can be used as a blocking peptide with polyclonal antibody PA5-20755.