(−)-Epicatechin
≥90% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 490-46-0
Synonym(S): (−)-cis-3,3′,4′,5,7-Pentahydroxyflavane, (2R,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 G | E1753-1-G | In Stock | ₹ 19,019.53 |
| 5 G | E1753-5-G | In Stock | ₹ 77,626.08 |
E1753 - 1 G
In Stock
Quantity
1
Base Price: ₹ 19,019.53
GST (18%): ₹ 3,423.515
Total Price: ₹ 22,443.045
Quality Level
200
Assay
≥90% (HPLC)
form
powder
mp
240 °C (dec.) (lit.)
application(s)
metabolomicsvitamins, nutraceuticals, and natural products
SMILES string
O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3
InChI
1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15-/m1/s1
InChI key
PFTAWBLQPZVEMU-UKRRQHHQSA-N
Gene Information
human ... BACE1(23621) , CYP1A2(1544)
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
(-)-Epicatechin, ≥97% (HPLC), MilliporeSigma™ Supelco™ | -- | ₹ 54,156.50 | ||
Sigma Aldrich Fine Chemicals Biosciences (-)-Epicatechin >=90% (HPLC) | 490-46-0 | MFCD00075648 | 1G | -- | ₹ 22,132.52 | ||
Sigma Aldrich Fine Chemicals Biosciences (−)-Epicatechin | 490-46-0 | MFCD00075648 | 5mg | -- | ₹ 22,350.57 | ||
(−)-Epicatechin | -- | ₹ 40,247.35 | ||
(−)-Epicatechin | -- | ₹ 40,517.98 | ||
Epicatechin | -- | ₹ 39,543.73 | ||
(−)-Epicatechin | -- | ₹ 23,836.65 | ||
(−)-Epicatechin | -- | ₹ 5,813.03 - ₹ 22,440.23 | ||
(-)-Epicatechin | -- | ₹ 1,424.00 - ₹ 36,846.00 |
Description
- General description: (−)-Epicatechin (EC) belongs to the group of flavanols and is abundantly present in cacao and cacao products.[1] The chemical structure of EC includes an oxygenated heterocycle with a 4-hydroxyl group linked with two aromatic rings.[1]
- Application: (−)-Epicatechin (EC) has been used:as an antioxidant to downregulate nicotinamide adenine dinucleotide phosphate hydrogen (NADPH) oxidase and improve insulin sensitivity in in vivo (high fat-fed mice) and in vitro (HepG2 cells) studies[2]to study its effect on blood pressure, nitric oxide synthase (NOS) activity and anxiety-like behavior on borderline hypertensive rat (BHR) models[3]to test its effect on neuronal survival in the hippocampus of middle-aged rats on swimming training, under oxidative stress[4] to study its antioxidant activity in dark chocolate[5]as a characteristic compound in polyphenols analysis[6]
- Biochem/physiol Actions: Epicatechin enhances the skeletal muscle structure in heart failure patients and minimizes cardiometabolic risks. It can be used for treating sarcopenia. Epicatechin reduces myostatin and β-galactosidase and increases the level of markers of muscle growth.[7]
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves