Itraconazole for system suitability
European Pharmacopoeia (EP) Reference Standard
Manufacturer: Sigma Aldrich
CAS Number: 84625-61-6
Synonym(S): Itraconazole, Oriconazole, R51211, Sporanox
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 15 MG | Y0001100-15-MG | In Stock | ₹ 14,267.35 |
Y0001100 - 15 MG
In Stock
Quantity
1
Base Price: ₹ 14,267.35
GST (18%): ₹ 2,568.123
Total Price: ₹ 16,835.473
grade
pharmaceutical primary standard
API family
itraconazole
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
CCC(C)N1N=CN(C1=O)c2ccc(cc2)N3CCN(CC3)c4ccc(OCC5COC(Cn6cncn6)(O5)c7ccc(Cl)cc7Cl)cc4
InChI
1S/C35H38Cl2N8O4/c1-3-25(2)45-34(46)44(24-40-45)29-7-5-27(6-8-29)41-14-16-42(17-15-41)28-9-11-30(12-10-28)47-19-31-20-48-35(49-31,21-43-23-38-22-39-43)32-13-4-26(36)18-33(32)37/h4-13,18,22-25,31H,3,14-17,19-21H2,1-2H3
InChI key
VHVPQPYKVGDNFY-UHFFFAOYSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ Itraconazole | -- | ₹ 8,766.50 | ||
MilliporeSigma™ Calbiochem™ Hh Signaling Antagonist X, Itraconazole | -- | ₹ 20,145.15 | ||
Sigma Aldrich Fine Chemicals Biosciences Itraconazole | 84625-61-6 | MFCD00870168 | 100mg | -- | ₹ 22,568.62 | ||
Sigma Aldrich Fine Chemicals Biosciences Itraconazole for system suitability European Pharmacopoeia (EP) Reference Standard | 84625-61-6 | MFCD00870168 | | -- | ₹ 17,007.90 | ||
Itraconazole Pharmaceutical Secondary Standard, MilliporeSigma™ Supelco™ | -- | ₹ 21,805.00 | ||
Sigma Aldrich Fine Chemicals Biosciences Itraconazole European Pharmacopoeia (EP) Reference Standard | 84625-61-6 | MFCD00870168 | | -- | ₹ 17,007.90 | ||
Itraconazole | -- | ₹ 21,108.75 | ||
Itraconazole | -- | ₹ 40,756.13 | ||
Itraconazole solution | -- | ₹ 10,879.40 | ||
Itraconazole | -- | ₹ 27,517.15 |
Related Products
Description
- General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
- Application: Itraconazole for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
- Biochem/physiol Actions: Itraconazole inhibits cytochrome P-450-dependent enzymes which results in the inhibition of ergosterol synthesis. It does so by interacting with 14-α demethylase, which is a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. Ergosterol is a crucial compenent of fungal cell membranes. Therefore, it′s inhibition results in increased cellular permeability causing leakage of cellular contents. Itraconazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and impair triglyceride and phospholipid biosynthesis.
- Packaging: The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
- Other Notes: Sales restrictions may apply.
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable