447714

Methylenebis(phosphonic dichloride)

97%

Manufacturer: Sigma Aldrich

CAS Number: 1499-29-2

Select a Size

Pack Size SKU Availability Price
5 G 447714-5-G In Stock ₹ 15,772.03

447714 - 5 G

₹ 15,772.03

In Stock

Quantity

1

Base Price: ₹ 15,772.03

GST (18%): ₹ 2,838.965

Total Price: ₹ 18,610.995

Quality Level

200

Assay

97%

form

solid

mp

102-104 °C (lit.)

SMILES string

ClP(Cl)(=O)CP(Cl)(Cl)=O

InChI

1S/CH2Cl4O2P2/c2-8(3,6)1-9(4,5)7/h1H2

InChI key

VRXYCDTWIOCJBH-UHFFFAOYSA-N

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Description

  • General description: Methylenebis(phosphonic dichloride) is an organophosphorus compound that is commonly used in phosphonylation reactions. It is more reactive and the rate of reaction is faster compared to POCl3. This is because the phosphorus center is more electrophilic due to the lack of electron back-donation from the CH2 group[1].
  • Application: Methylenebis(phosphonic dichloride) may be used for the following studies:Synthesis of mycophenolic methylenebis(phosphonate) derivatives.[2]Phosphonylation of nucleosides.[1]Preparation of P,P′-partial esters of methylenebisphosphonic acid.[3]Synthesis of symmetrical di- and tetra- esters of methylenebisphosphonic acid.[4]

SAFETY INFORMATION

Pictograms

GHS05

Signal Word

Danger

Hazard Statements

H314

Precautionary Statements

P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Supplementary Hazards

EUH014

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves