78-521-0
Tocris Bioscience™ EM12-SO2F
Manufacturer: Tocris Bioscience™
CAS Number: 2803819-61-4
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 78-521-0-Each-of-1 | In Stock | ₹ 12,842.70 |
78-521-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,842.70
GST (18%): ₹ 2,311.686
Total Price: ₹ 15,154.386
Chemical Name or Material
2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-3-oxo-1H-isoindole-5-sulfonyl fluoride
Quantity
10 mg
Molecular Formula
C13H11FN2O5S
CAS
2803819-61-4
Target
CRBN
Purity
95%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
EM12-SO2F | -- | ₹ 6,675.00 - ₹ 75,205.00 | ||
2803819-61-4 | 2-(2,6-dioxopiperidin-3-yl)-3-oxoisoindoline-5-sulfonyl fluoride | -- | ₹ 6,052.00 - ₹ 39,160.00 |
Related Products
Description
- EM12-SO2F is a potent covalent Cereblon (CRBN) inhibitor (IC50 = 0.88 nM)
- Binds to a histidine residue (His353) in the IMiD binding pocket of CRBN and blocks the recruitment of its substrates
- EM12-SO2F prevents Lenalidomide (Cat
- No
- 6305)-induced degradation of the zinc finger transcription factor IKZF1 in MOLT4 cells
- It complements CRBN based PROTAC and genetic methods to validate CRBN-mediated degradation.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C