K1616

Thermo Scientific™ Tango™ GALR1-blaU2OS Cells

Manufacturer: Thermo Scientific™

Select a Size

Pack Size SKU Availability Price
Each of 1 K1616-Each-of-1 In Stock ₹ 9,41,620.00

K1616 - Each of 1

₹ 9,41,620.00

In Stock

Quantity

1

Base Price: ₹ 9,41,620.00

GST (18%): ₹ 1,69,491.60

Total Price: ₹ 11,11,111.60

Accession Number

NM_001480

Cell State

Dividing Cells

Cytoplasmic Tail

Tail from AVPR2 GPCR

Gene Symbol

GALR1

Product Line

GeneBLAzer™

Quantity

8 x 106Cells

Reporter Gene

BLA (Beta-Lactamase)

Cell Line

U2OS

Druggable Target

GPCR

Assay Entry

Cell-based beta-arrestin recruitment

Content And Storage

LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes• Tango™ GALR1-bla U2OS cells• Tango™ GALR1-bla U2OS Assay Protocol• Certificate of AnalysisThe Tango™ GALR1-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method

Fluorescence

Population Status

Pool of Stable Cells

Protein Family

GPCR (G-Protein Coupled Receptors)

Readout

End Point

Target Entry

GALR1

System Type

Tango™

Related Products

Img

Thermo Scientific™

K1782

--

Img

Thermo Scientific™

K1562

--

Img

Thermo Scientific™

K1543

--

Img

Thermo Scientific™

K1777

--

Img

Thermo Scientific™

K1754

--

Img

Thermo Scientific™

K1801

--

Img

Thermo Scientific™

K1809

--

Img

Thermo Scientific™

K1518

--

Description

  • The Tango™ GALR1 -bla U2OS cells contain the human Galanin Receptor 1 (GALR1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line
  • This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element
  • The Tango™ GALR1-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of established ligands
  • In addition, Tango™ GALR1-bla U2OS cells have been tested for assay performance under variable conditions
  • These data are found in the Validation & Assay Performance Summary for each product.