Description

• General description: Cholecalciferol (D3) is a fat soluble vitamin, and is one of the forms of vitamin D, synthesized in human skin on exposure to ultraviolet (UV) radiation from sunlight, or it can also be obtained from food.[1][2] It is found to be essential in humans for maintaining normal calcium metabolism.[2]
• Application: Cholecalciferol (D3) may be used as an analytical reference for the quantification of the analyte in different food matrices[1][2] using different chromatography techniques.
• Biochem/physiol Actions: Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis.
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