F9505

Furazolidone

Manufacturer: Sigma Aldrich

CAS Number: 67-45-8

Synonym(S): 3-(5-Nitrofurfurylideneamino)-2-oxazolidinone

Select a Size

Pack Size SKU Availability Price
10 G F9505-10-G In Stock ₹ 7,826.48

F9505 - 10 G

₹ 7,826.48

In Stock

Quantity

1

Base Price: ₹ 7,826.48

GST (18%): ₹ 1,408.766

Total Price: ₹ 9,235.246

biological source

synthetic

Quality Level

200

form

powder

color

yellow

mp

256-256 °C

solubility

formic acid: 50 mg/mL

antibiotic activity spectrum

Gram-positive bacteriaparasites

Mode of action

enzyme | inhibits

SMILES string

[O-][N+](=O)c1ccc(\C=N\N2CCOC2=O)o1

InChI

1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2/b9-5+

Other Options

Image Product Name Manufacturer Price Range
VETRANAL™ Furazolidone, MilliporeSigma™ Supelco™
-- ₹ 7,921.00
Furazolidone
-- ₹ 20,394.30
Furazolidone
-- ₹ 39,154.03
Furazolidone
-- ₹ 7,826.48
Furazolidone
-- ₹ 4,272.00 - ₹ 71,378.00

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Description

  • Application: Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone binds bacterial DNA, which leads to the gradual inhibition of monoamine oxidase. It is used to treat anorexia and antagonism of thiamin utilization in poultry[1]. Furazolidone increases thapsigargin-sensitive Ca2+-ATPase in chick cardiac myocytes[2].
  • Biochem/physiol Actions: Furazolidone and its generated free radicals, may bind to DNA and induce cross-links. Bacterial DNA is particularly susceptible to this drug, which results in high levels of mutations (transitions and transversions) in the bacterial chromosome. Its mechanism of action minimizes the development of resistant organisms. Furazolidone is a monoamine oxidase (MAO) inhibitor and is used as a DNA interstrand cross-linking agent.

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Warning

Hazard Statements

H361fd

Precautionary Statements

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 2

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves