I4657
Insulin-like Growth Factor-I Receptor human
≥95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder
Manufacturer: Sigma Aldrich
Synonym(S): IGF-I Receptor
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 μG | I4657-50-μG | In Stock | ₹ 1,03,956.20 |
I4657 - 50 μG
In Stock
Quantity
1
Base Price: ₹ 1,03,956.20
GST (18%): ₹ 18,712.116
Total Price: ₹ 1,22,668.316
biological source
human
Quality Level
200
recombinant
expressed in NSO cells
Assay
≥95% (SDS-PAGE)
form
lyophilized powder
mol wt
α-chain ~120 & 150 kDaβ subunit ~46 & 50 kDa
packaging
pkg of 50 μg
impurities
endotoxin, tested
UniProt accession no.
P08069
storage temp.
−20°C
Related Products
Description
- General description: IGF1R (insulin-like growth factor I) is a receptor tyrosine kinase.[1] The gene is mapped to human chromosome 15q26.[2] It is expressed in various solid tumors as well as hematologic malignancies.[3]
- Application: Insulin-like growth factor-I receptor human has been used to study the binding constants of estradiol to insulin, insulin receptors and insulin-like peptides.[4]
- Biochem/physiol Actions: IGF-I receptor, a tyrosine kinase receptor with signal transduction pathways, is comprised of two α and two β subunits. IGF-I receptor binds IGF-I with high affinity, IGF-II with lower affinity, and insulin with weak affinity.
- Physical form: Lyophilized from a 0.2 μm solution in phosphate buffered saline.
- Analysis Note: As a result of glycosylation in SDS-PAGE under reducing conditions, the recombinant α subunit migrates as a doublet of ~120 kDa and 150 kDa and the β subunit migrates as doublet of ~46 kDa and 50 kDa.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves