I7908

Interleukin-2 human

recombinant, expressed in Pichia pastoris, suitable for cell culture

Manufacturer: Sigma Aldrich

Synonym(S): IL-2, Interleukin-2, T-cell growth factor

Select a Size

Pack Size SKU Availability Price
10000 UNITS I7908-10000-UNITS In Stock ₹ 32,811.60

I7908 - 10000 UNITS

₹ 32,811.60

In Stock

Quantity

1

Base Price: ₹ 32,811.60

GST (18%): ₹ 5,906.088

Total Price: ₹ 38,717.688

biological source

human

Quality Level

200

recombinant

expressed in Pichia pastoris

Assay

≥98% (SDS-PAGE and HPLC)

form

lyophilized powder

mol wt

predicted mol wt ~15 kDa

packaging

pkg of 10KU

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

UniProt accession no.

P60568

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Description

  • Application: Interleukin-2 human has been used to assess changes in tumor necrosis factor receptor 1 (TNFR1). It has also been used in TNFR2 expression on Tregs.[1]
  • Biochem/physiol Actions: Interleukin 2 (IL2) is a pro-inflammatory cytokine.[2] It consists of three subunits, in which the β subunit is important for receptor mediated signaling.[3] IL2 enhances the development of T regulatory cells[4] and plays a crucial role in antitumor immunity.[2]
  • Physical form: Lyophilized from a 0.2 μm filtered solution in 50 mM sodium phosphate buffer, pH 7.0, containing 0.1% human serum albumin per 0.1 mL of cytokine.
  • Analysis Note: The biological activity is tested in a cell proliferation assay using an IL-2 dependent murine cytotoxic T cell line, CTLL-2.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves