PHR1432

N-Acetylglucosamine

Pharmaceutical Secondary Standard; Certified Reference Material

Manufacturer: Supelco

CAS Number: 7512-17-6

Synonym(S): N-Acetyl-D-glucosamine, 2-Acetamido-2-deoxy-D-glucose, D-GlcNAc

Select a Size

Pack Size SKU Availability Price
1 G PHR1432-1-G In Stock ₹ 10,911.60

PHR1432 - 1 G

₹ 10,911.60

In Stock

Quantity

1

Base Price: ₹ 10,911.60

GST (18%): ₹ 1,964.088

Total Price: ₹ 12,875.688

grade

certified reference materialpharmaceutical secondary standard

Quality Level

300

Agency

traceable to USP 1010022

API family

glucosamine

CofA

current certificate can be downloaded

technique(s)

HPLC: suitablegas chromatography (GC): suitable

mp

211 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

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Description

  • General description: N-Acetylglucosamine (GlcNAc) is a monosaccharide, derived from glucose and undergoes linear polymerization by (1,4)-β-linkages to form the polymer chitin. It is also a component of heterogenous polysaccharides, such as murein and hyaluronic acid.[1] N-acetylglucosamine exhibits anti-inflammatory properties and is considered as a potential drug in the treatment of osteoarthritis. Its antiarthritic mode of mechanism involves the suppression of IL-1β (Interleuken-1β)-induced NO (nitric oxide), cyclooxygenase-2 (COX-2), and IL-6 production by inhibition of expression of iNOS (inducible nitric oxide synthase) protein and mRNA.[2]Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
  • Application: N-Acetylglucosamine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometric, chromatographic,[3] and electrophoretic[4] techniques.
  • Analysis Note: These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
  • Other Notes: This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
  • Footnote: To see an example of a Certificate of Analysis for this material enter LRAC3267 in the slot below. This is an example certificate only and may not be the lot that you receive.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable