50937

Guanidine hydrochloride solution

Manufacturer: Sigma Aldrich

CAS Number: 50-01-1

Synonym(S): Aminoformamidine hydrochloride, Guanidinium chloride, Guanidium chloride

Select a Size

Pack Size SKU Availability Price
100 ML 50937-100-ML In Stock ₹ 20,805.65

50937 - 100 ML

₹ 20,805.65

In Stock

Quantity

1

Base Price: ₹ 20,805.65

GST (18%): ₹ 3,745.017

Total Price: ₹ 24,550.667

product line

BioUltra

Quality Level

100

form

liquid

concentration

~8 M in H2O

impurities

insoluble matter, passes filter test

refractive index

n20/D 1.465

pH

4.5-7.5 (25 °C)

anion traces

sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤1 mg/kgAs: ≤0.1 mg/kgBa: ≤1 mg/kgBi: ≤1 mg/kgCa: ≤5 mg/kgCd: ≤1 mg/kgCo: ≤1 mg/kgCr: ≤1 mg/kgCu: ≤1 mg/kgFe: ≤1 mg/kgK: ≤20 mg/kgLi: ≤1 mg/kgMg: ≤1 mg/kgMn: ≤1 mg/kgMo: ≤1 mg/kgNa: ≤60 mg/kgNi: ≤1 mg/kgPb: ≤1 mg/kgSr: ≤1 mg/kgZn: ≤1 mg/kg

λ

neat

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Description

  • Application: Guanidine hydrochloride solution has been used as a fixation buffer in genomic DNA extraction for genomic analysis.[1]
  • Biochem/physiol Actions: Guanidine‐HCl (Gnd-HCl), an efficient chaotropic agent, is broadly used in RNA isolation, globular protein denaturation, and protein refolding studies as a denaturant. It is an appropriate sample buffer for the quick and effective elution of affinity-purified protein complexes and the subsequent protein digestion step.[2] Gnd-HCl is not preferred in proteomics experiments due to its hindrance with trypsin activity at low molar concentrations and tendency to precipitate when combined with sodium dodecyl sulfate (SDS).[2] GnHCl is commonly utilized to extract proteins in extracellular matrix (ECM)‐rich tissues including bone, cartilage, ligament, and tendon.[3]

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H302 + H332,H315,H319

Precautionary Statements

P261 - P264 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves